Let

be a module over a commutative ring and let

be the
collection of all prime submodules of

. One can define a Zariski
topology on

, which is analogous to that on

, and
then for any non-empty set

of

, it is possible to
define a simple graph

, called the Zariski
topology-graph. In this paper, we study the domination number of

and some connections between the graph-theoretic
properties of

and algebraic properties of the module

.